1-tert-(Butoxycarbonyl)pyrrolidin-4-one-2-carboxylic acid
1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid
CAS: 876317-19-0
Molecular Formula: C10H15NO5
1-tert-(Butoxycarbonyl)pyrrolidin-4-one-2-carboxylic acid - Names and Identifiers
1-tert-(Butoxycarbonyl)pyrrolidin-4-one-2-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C10H15NO5 |
| Molar Mass | 229.23 |
| Density | 1.304±0.06 g/cm3(Predicted) |
| Melting Point | 155 °C |
| Boling Point | 390.8±42.0 °C(Predicted) |
| Flash Point | 190.123°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 3.85±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.516 |
1-tert-(Butoxycarbonyl)pyrrolidin-4-one-2-carboxylic acid - Introduction
1-(tert-butoxycarbonyl)-acid is an organic compound with the chemical formula C10H15NO4.
Properties: 1-(tert-butoxycarbonyl)-acid is a white crystalline solid, stable at room temperature. It is soluble in organic solvents such as dimethyl sulfoxide and practically insoluble in water.
use: 1-(tert-butoxycarbonyl)-acid is often used as a protecting group in organic synthesis, and can be added to the compound through acylation reaction to protect the carboxylic acid group in the reaction. In the field of synthetic peptides and pharmaceuticals, it is widely used to protect amino acids and carboxylic acids of polypeptides to prevent unwanted reactions from occurring.
Preparation method: 1-(tert-butoxycarbonyl)-The preparation of acid is generally obtained by reacting pyrrolidine-2-carboxylic acid with a tert-butoxycarbonylation agent. The reaction is usually carried out under an inert atmosphere to avoid the influence of oxygen in the air.
Safety information: 1-(tert-butoxycarbonyl)-The acid is generally relatively safe under normal use conditions. However, as an organic compound, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, personal protective measures should be taken to avoid direct contact during handling and use. At the same time, follow the safe operation procedures of the laboratory to prevent accidental ingestion and inhalation, and store properly, away from fire and oxidant. In case of accidental exposure or discomfort, medical help should be sought immediately.
Properties: 1-(tert-butoxycarbonyl)-acid is a white crystalline solid, stable at room temperature. It is soluble in organic solvents such as dimethyl sulfoxide and practically insoluble in water.
use: 1-(tert-butoxycarbonyl)-acid is often used as a protecting group in organic synthesis, and can be added to the compound through acylation reaction to protect the carboxylic acid group in the reaction. In the field of synthetic peptides and pharmaceuticals, it is widely used to protect amino acids and carboxylic acids of polypeptides to prevent unwanted reactions from occurring.
Preparation method: 1-(tert-butoxycarbonyl)-The preparation of acid is generally obtained by reacting pyrrolidine-2-carboxylic acid with a tert-butoxycarbonylation agent. The reaction is usually carried out under an inert atmosphere to avoid the influence of oxygen in the air.
Safety information: 1-(tert-butoxycarbonyl)-The acid is generally relatively safe under normal use conditions. However, as an organic compound, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, personal protective measures should be taken to avoid direct contact during handling and use. At the same time, follow the safe operation procedures of the laboratory to prevent accidental ingestion and inhalation, and store properly, away from fire and oxidant. In case of accidental exposure or discomfort, medical help should be sought immediately.
Last Update：2024-04-09 21:11:58
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Product Name: 1-(Tert-Butoxycarbonyl)-4-Oxopyrrolidine-2-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 876317-19-0
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Mobile: 18021002903
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CAS: 876317-19-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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